Chicopee ) is a city located on the Connecticut River in Hampden County, Massachusetts, United States of America. It is part of the Springfield, Massachusetts Metropolitan Statistical Area. As of the 2010 census, the city had a total population of 55,298, making it the second largest city in Western Massachusetts after Springfield. The current mayor is Michael D. Bissonnette.Chicopee uses the nickname “Crossroads of New England” as part of a business-development marketing campaign. The name reflects the city's convenient location amongst a number of metropolitan areas and its transportation network. Four highways run through its boundaries: I-90, I-91, I-291, and I-391. State routes such as Route 33, 116, and 141, are major providers of regional linkage.