Columbus is a city in Lowndes County, Mississippi, United States that lies above the Tombigbee River. It is approximately 282 km northeast of Jackson, 193 km north of Meridian, 102 km south of Tupelo, (60 mi) northwest of Tuscaloosa, Alabama, and 198 km west of Birmingham, Alabama. The population was 25,944 at the 2000 census. It is the county seat of Lowndes County and the principal city of the Columbus Micropolitan Statistical Area, which is part of the larger Columbus-West Point Combined Statistical Area. Columbus is also part of the area of northeast Mississippi called The Golden Triangle, consisting of Columbus, West Point and Starkville, in the counties of Lowndes, Clay and Oktibbeha.