Dubuque ) is a city in and the county seat of Dubuque County, Iowa, United States, located along the Mississippi River. In 2010 its population was 57,637, making it the ninth-largest city in the state and the county's population was 93,653.The city lies at the junction of three states: Iowa, Illinois, and Wisconsin, a region locally known as the Tri-State Area. It serves as the main commercial, industrial, educational, and cultural center for the area. Geographically, it is part of the Driftless Area, a portion of North America that escaped all three phases of the Wisconsinian Glaciation.It is one of the few large cities in Iowa with hills, and is home to a large tourist industry, driven by the city's unique architecture, and river location. Also, it is home to five institutions of higher education, making it a center for culture and learning.While Dubuque has long been a center of manufacturing, the economy has recently witnessed rapid growth and diversification in other areas. In 2005, it led the state and the Midwest in job growth, ranking as the 22nd fastest-growing economy nationally. Today, alongside industry, the city has large health care, education, tourism, publishing, and financial service sectors.